摘要
过去人们一直认为细胞死亡存在坏死和凋亡两种方式,近年来随着研究的进展,研究者先后发现体内还存在其他的细胞死亡方式。目前对于细胞死亡方式及它们之间存在的相互联系尚不十分清楚,尤其对神经细胞死亡方式的研究更加有限。本文主要对缺血性脑卒中过程中几种常见的神经细胞死亡方式及相互联系作一综述,以期为神经细胞死亡的进一步研究提供一定的理论基础,为缺血性脑卒中的治疗提供新的思路。
It was believed that there were only two patterns of cell death named after necrosis and apoptosis in the past. With the progress of research, scholars have found that there also existed other cell death patterns. However, the mechanisms and relationships between cell death patterns are still unclear, especially in the neuronal cell death. This review focuses on the cell death patterns and their relationships during ischemic stroke, in order to provide the theoretical basis and new ideas for the further study of neuronal cell death, and for the treatment of ischemic stroke.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2016年第8期902-906,共5页
Chinese Journal of Geriatrics
基金
国家自然基金面上资助项目(81371298)
吉林省自然科学基金项目(20160101099)
关键词
卒中
脑缺血
细胞凋亡
坏死
自噬
细胞死亡
stroke
Brain ischemia
Apoptosis
Necrosis
Autophagy
Cell death