高血压病伴焦虑障碍患者血压变异性的研究进展

Research progress of blood pressure variability of hypertensive patients with anxiety disorders

原发性高血压是常见的心血管病,血压的波动影响心脑血管事件的发生。焦虑障碍可以引起血压昼夜节律变化,是高血压促发与加重的重要因素之一,影响降压药物疗效,从而不利于高血压的预后。高血压和焦虑障碍均能在一定程度上影响自主神经功能,造成血压波动,影响血压变异性。高血压伴焦虑障碍患者通过两种疾病的相互作用可能会加重血压变异,造成血压变化节律的紊乱。对原发性高血压伴焦虑障碍患者同时进行降压治疗和抗焦虑治疗可能改善血压变异性,降低心脑血管事件的发生率,从而更好地改善预后。

Essential hypertension is a common cardiovascular disease, and blood pressure fluctuation affects the occurrence of cardiovascular and cerebrovaseular events. Anxiety disorders may cause changes of diurnal rhythm of blood pressure, which is one of important factors of developing and aggravating hypertension, affecting efficacy of anti-hypertensive drug, thus not benefit for prognosis. Hypertension and anxiety disorders both can influence autonomic nervous function to some extent,leading to fluctuation of blood pressure, affecting blood pressure variability. Hypertension patients with anxiety disorders may have exacerbation of blood pressure variability by the interaction of two conditions, resulting in dysrhythmia of blood pressure changes. For hypertension patients with anxiety disorders eonducting antihypertensive therapy and antianxiety therapy at the same time may improve blood pressure variability, reduce incidence rates of cardiovascular and cerebrovascular events, thus better improve prognosis.