摘要
目的:探讨神经白塞氏病(NBD)的临床特征及诊治方法。方法:收集本院风湿科从2005年至2014年收治的13例NBD患者,回顾性分析患者的临床资料。结果:NBD临床表现包括头痛(9例),发热(7例),精神症状(4例),肢体瘫痪、麻木(3例),共济失调(2例),构音障碍(1例)及眩晕(1例)。头颅MRI提示病变部位主要分布在中脑(5例)、脑桥(2例)及基底节区(2例)。患者均给予糖皮质激素免和疫抑制剂后症状缓解。结论:NBD预后较差,为白塞氏病的重症表现之一。了解NBD的临床特征,有利于对该类患者进行及早的诊断与治疗。
Objective:To summarize on the clinical features, diagnosis and treatment of Neuro-Behcet′s disease ( NBD) . Methods:A retrospective analysis was performed on clinical data from 13 NBD patients treated in our Department of Rheumatology and Immunology between 2005 and 2014. Results:Clinical manifestations of NBD included headache (n=9),fever (n=7),mental disorders (n=4),paralysis or numbness of limbs (n=3) ,ataxia ( n=2) ,dysarthria ( n=1) and vertigo ( n=1) . Cranial MRI showed that the lesions mainly involved the mid-brain ( n=5) ,pons ( n=2) and basal ganglia ( n=2) . All patients were symptomatically relieved after treated with corticosteroids and immunosuppressants. Conclusion:NBD is poor in prognosis, and represents a severe form of Behcet′s disease. Understanding the clinical features of NBD may help early diagnosis and treatment of these patients.
出处
《广州医科大学学报》
2016年第3期92-94,共3页
Academic Journal of Guangzhou Medical University
关键词
白塞氏病
神经白塞氏病
临床特征
糖皮质激素
免疫抑制剂
Behcet′s disease
Neuro-Behcet′s disease
clinical features
corticosteroid
immunosuppressant