滇藏杜英化学成分研究

Chemical Constituents from Elaeocarpus braceanus

通过有机溶剂提取、色谱等手段从滇藏杜英(Elaeocarpus braceanus)分离到17个化合物,根据氢谱(1H NMR)、碳谱(13C NMR)、质谱(MS)等波谱解鉴定分别为3-氨基4-羟基-苯甲酸-1-O-β-D-吡喃木糖甙(1)、3,5,7-三羟基-4'-甲氧基黄酮(2)、杨梅素(3)、5-O-甲基-杨梅素(4)、4'-O-甲基-杨梅素(5)、二氢山奈酚(6)、二氢杨梅素(7)、杨梅素3-O-α-L-鼠李糖甙(8)、山奈酚-3-O-α-L-鼠李糖甙(9)、4'-O甲基-杨梅素3-O-α-L-鼠李糖甙(10)、7,4'-O–二甲基杨梅素3-O-α-L-鼠李糖甙(11)、4'-O–甲基杨梅素3-O-β-D-葡萄糖甙(12)、山奈酚-3-O-β-D-葡萄糖甙(13)、(3β,9β,10α,16α,23R)-16,23-epoxy-3-(β-D-glucopyranosyloxy)-20-hydroxy-9-methyl-19-norlanosta-5,24-dien-11-one(14)、β-谷甾醇(15)、β-胡萝卜甙(16)和3,5-二羟基4-甲氧基苯甲酸(17),其中1为新化合物,其它16个化合物是首次从滇藏杜英中发现。

The chemical components of Elaeocarpus braceanus were extracted using organic solvent extraction. Column chromatography led to the isolation of 17 compounds. Combination of the 1D-,2D-NMR and mass spectrometry, all com- pounds were identified as 3-amino-4-hydroxybenzoate-1 -O-β-D-xylopyranoside （ 1 ）, 3,5,7-trihydroxy-4＇-methoxyflavone （ 2 ）, myricetin （ 3 ）, 5 -O-methyl-myricetin （ 4 ）, 4＇-O-methyl-myricetin （ 5 ）, 3,5,7,4＇-tetrahydroxy-2,3-dihydroflavone （6）, dihydromyricetin （ 7 ）, myrieetin 3-O-α-L-rhamnopyranoside （ 8 ）, Kaempferol-3-O-α-L-rhamnoside （ 9 ）, 4＇-0- methyl-myricetin 3-O-α-L-rhamnoside （ 10）, 7,4＇-O-dimethyl-myricetin 3-O-α-L-rhamnoside （ 11 ）, 4＇-O-methyl-myr- icetin 3-O-β-D-glucoside （ 12 ）, Kaempferol 3-O-β-D-glucoside （ 13 ）, （ 3β,9β, 10α, 16α, 23R ） -16,23-epoxy-3 - （β-D- glucopyranosyloxy） -20 -hydroxy-9-methyl-19 -norlanosta-5,24-dien-11 -one （ 14 ） ,13-sitosterol （ 15 ）, daucosterol （ 16 ）, 3, 5-dihydroxy-4-methoxybenzoic acid （17）. Additionally, 1 was a new compound, and other 16 compounds were firstly iso- lated from the titled plant.