帕金森病认知功能障碍患者中医证型分布规律

TCM Syndrome distribution of PD-MCI cognition impairment

目的了解帕金森病(PD)轻度认知功能障碍(PD-MCI)的证候分布规律。方法对102例PD-MCI的患者进行西医分期,同时进行中医辨证,了解其证候分布规律。结果 102例中,髓海不足证51例(50.00%)、瘀证44例(43.14%)、痰证36例(35.29%),出现率最高。证候组合形态以髓海不足血瘀证最多,21例(20.59%);且分期不同,髓海不足证、瘀证、痰证出现率始终较高,中期及晚期PD患者气虚及髓海不足出现率增高,风热痰瘀各证出现率减少。结论髓海不足,痰瘀阻络为PD-MCI的主要病机,证型的变化与PD轻重分期密切相关。

Objective To explore the TCM syndrome distribution of parkinson disease-Mild cognitive impairment （PD-MCI）.Methods Western medicine stages are applied to 102 patients of PD-MCI,while TCM syndrome distribution was also observed.Results Among the 102 patients,the TCM syndrome distribution was as follows sui asthenia 51 cases （50.00％）,blood stasis 44 cases （43.14％）,and phlegm-dampness 36 cases （35.29％）,Sui asthenia and blood stasis type is the most 21 cases （20.59％） among the 102 patients.The Sui asthenia,blood stasis and phlegmdampness are in the every stage of disease,qi asthenia and Sui asthenia were occupying larger and larger percentage in the development of disease;Sui asthenia,blood stasis and phlegm-dampnes were involved in the whole process of disease.Conclusion Sui asthenia,blood stasis and phlegm-dampnes were the most important in the PD-MCI,there has relationship between the changing of TCM Syndromes and stages.