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老年急性冠脉综合征患者冠脉狭窄和脂质代谢紊乱程度与幽门螺杆菌感染的相关性 被引量:13

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摘要 目的探讨幽门螺杆菌(Hp)与老年急性冠脉综合征(ACS)患者冠脉狭窄程度及血脂代谢异常的相关性。方法选取该院2012年5月至2015年5月收治的187例老年ACS患者纳入观察组,同期150例老年非ACS受试者纳入对照组。根据“c尿素呼气试验,比较两组受试者Hp感染率,分析阴性感染、轻度感染、重度感染老年ACS患者冠状动脉狭窄程度及血脂代谢水平的差异。结果观察组患者Hp感染率、感染程度均显著高于对照组(P〈0.05)。随着患者Hp感染程度的加重,其Gensini评分、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL—C)水平逐渐升高(P〈0.05)。Pearson相关分析示,14c每分钟衰变数与老年ACS患者Gensini评分、TC、TC、LDL—C水平均呈正相关(P〈0.05),14C每分钟衰变数与高密度脂蛋白胆固醇(HDL—C)无明显相关性(P〉0.05)。结论Hp可通过影响机体血脂代谢水平,促进动脉粥样硬化形成,加剧老年ACS患者冠脉狭窄程度。
作者 张鸿雁
出处 《中国老年学杂志》 CAS CSCD 北大核心 2016年第16期3951-3952,共2页 Chinese Journal of Gerontology
基金 2014年山东省自然科学基金(No.2014ZRB14219)
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参考文献10

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