序贯器官衰竭评分评估重度子痫前期患者的回顾性分析

Retrospective Analysis of Sequential Organ Failure Assessment in Patients With Severe Preeclampsia

目的探讨序贯器官衰竭评分（SOFA）在评估重度子痫前期（SPE）患者病情危重程度中的价值。方法选取57例SPE患者，按照病情及干预措施分为危重组35例和对照组22例，比较两组患者的初始SOFA评分及最高SOFA评分，分析SOFA评分对疾病严重程度的预测价值。结果与对照组相比，危重组的初始SOFA评分[（5．5±2．1）VS．（34±13），t=323，P〈0051及最高SOFA评分[（98±3．5）vs．（59±22），t=298，P〈0．05]均明显升高。初始SOFA评分评估病情危重的曲线下面积为0772（95％CI 0．605～0954，P〈0．05），其敏感度为736％，特异度为825％；最高SOFA评分评估病情危重的曲线下面积为0.895（95％C70．724～0．983，P〈0．05），其敏感度为922％，特异度为88．3％。结论早期动态监测SOFA评分是判断SPE患者疾病严重程度的良好方法。

Objective To investigate the value of sequential organ failure assessment score （SOFA） accessing the patients with severe preeclampsia. Methods 57 patients with severe preeclampsia （SPE） were retrospectively selected. They were divided into critical group with 35 cases and control group with 22 cases by severity of SPE and treatment measures. We compared the initial and maximum SOFA score in the two groups. The value of SOFA scot accessing the severity of SPE was analyzed. Results Compared with control group, critical group led to a greater increase in initial SOFA score [（5.5±2.1） vs. （3.4M.3）, t=-3.23,P〈0.05] and maximum SOFA score [（9.8±3.5） vs. （5.9±2.2）, t=2.98, P〈0.05]. The area under ROC curve of initial SOFA score was 0.772 （95% CI 0.605-0.954, P〈0.05）. The sensitivity and specificity were 73.6% and 82.5%. The area under ROC curve of maximum SOFA score was 0.895 （95% CI 0.724-0.983, P〈0.05）. The sensitivity and specificity were 92.2% and 88.3%. Conclusion Early and dynamic monitoring the SOFA score was a good method for evaluting the severity of SPE.