临床研究抗苗勒氏管激素AMH对卵巢囊肿术后患者卵巢储备能力的检测价值

Detection of Ovarian Reserve Capacity in Patients with Ovarian Cyst after Treatment with Anti- vaccine AMH

目的探讨抗苗勒氏管激素AMH对卵巢囊肿术后患者卵巢储备能力的检测价值。方法方便选择该院2014年1月—2015年1月施行卵巢囊肿手术患者50例,采用酶联免疫法检测患者术前术后AMH水平,比较各组(卵巢巧克力囊肿组和非巧克力囊肿组、双侧囊肿组和单侧囊肿组、囊肿直径>5cm组和直径<5 cm组)术前术后AMH指标检测值。结果 1与术前(2.5±1.9)对比,巧克力囊肿组患者术后AMH水平(1.3±0.5)明显下降,P<0.05;非巧克力囊肿组术前术后AMH水平比较差异无统计学意义,P>0.05。治疗后,与非巧克力囊肿组(2.1±0.8)对比,巧克力囊肿组AMH水平(1.3±0.5)明显更低,P<0.05。术前两组AMH水平差异无统计学意义,P>0.05。2与术前双侧(2.3±0.6)、单侧(2.1±0.3)对比,两组术后AMH水平双侧(0.8±0.3)、单侧(1.2±0.5)明显下降,P<0.05。治疗后,与单侧囊肿组(1.2±0.5)对比,术后双侧囊肿组AMH水平(0.8±0.3)明显更低,P<0.05。术前两组AMH水平差异无统计学意义,P>0.05。3与术前(2.2±0.5)、(2.1±0.2)对比,两组术后AMH水平(0.6±0.3)、(0.8±0.2)明显下降,P<0.05。治疗后,与囊肿直径<5 cm组(0.8±0.2)对比,术后囊肿直径>5 cm组AMH水平(0.6±0.3)明显更低,P<0.05。术前两组AMH水平差异无统计学意义,P>0.05。结论抗苗勒氏管激素AMH能够对卵巢囊肿术后患者卵巢储备能力进行可靠的预测,值得临床诊疗广泛应用。

Objective To observe the value of AMH in the detection of ovarian reserve in patients with ovarian cyst after operation. Methods Convenient selection choose our hospital in January 2014 to January 2015, 50 patients with ovarian cyst surgery by enzyme-linked immunoassay detection in patients with preoperative postoperative AMH level, comparison between groups （group of ovarian chocolate cyst and chocolate cyst, bilateral cyst group and unilateral cyst, cyst diameter〉5 cm group and diameter〈5 cm）, preoperative postoperative AMH index values. Results①compared with preoperative （2.5 ± 1.9）, chocolate cyst patients postoperative AMH level （1.3 ± 0.5） significantly decreased, P〈0.05;The chocolate cyst group there was no statistically significant difference compared preoperative postoperative AMH level, P〉 0.05. Group after treat-ment, with the chocolate cyst （2.1± 0.8）, chocolate cyst group of AMH level （1.3 ± 0.5） significantly lower,（P〈 0.05）. Pre-operative AMH level there was no significant difference in both groups, P〉 0.05. ② Compared with before （2.3 ± 0.6 on both sides, one side （2.1±0.3）, two groups of postoperative AMH level （0.8±0.3） on both sides, one side （1.2±0.5） signifi-cantly decreased, P〈 0.05）. Compared with single cyst group （1.2 ± 0.5）, postoperative bilateral AMH level （0.8 ±0.3） cyst group was obviously lower, P〈 0.05. Preoperative AMH level there was no significant difference in both groups, P〉 0.05.③Compared with before （2.2 ± 0.5）,（0.5 ± 0.2）, two groups of postoperative AMH level （0.6±0.3）,（0.3±0.2） significantly decreased, P〈0.05. After treatment, and cyst diameter 〈 5 cm group （0.8 ± 0.2）, postoperative cyst diameter 〉 5 cm group AMH level （0.6 ± 0.3） significantly lower, （P〈 0.05）. Preoperative AMH level there was no significant difference in both groups （P〉 0.05）.Conclusion The anti - vaccine of AMH can be used to predict the ovarian reserve capacity in patients with ovarian cyst after operation, and it is worth to be widely used in clinical diagnosis and treatment.