替吉奥胶囊联合紫杉醇治疗术后复发或转移性胃癌的疗效分析

To Observe the Curative Effect of S-1 Combined Paclitaxel in the Treat-ment of Postoperative Recurrence or Metastasis of Gastric Cancer

目的探究在术后复发或转移性胃癌治疗中采用替吉奥胶囊与紫杉醇联合治疗的临床治疗效果。方法方便选取该院在2011年10月—2015年10月期间收治的复发或转移性胃癌患者30例作为研究对象,所有患者均给予替吉奥胶囊与紫杉醇联合治疗,对其治疗总有效率进行观察和分析。结果经过联合治疗,患者完全缓解率为10.00%;部分缓解率为43.33%;稳定率为23.33%,病情进展率为23.33%,治疗总有效率为53.33%,不良反应包括胃肠道反应、周围神经毒性、骨髓抑制。结论在复发或转移性胃癌治疗中给予替吉奥胶囊与紫杉醇联合治疗效果较为理想,不良反应较轻,具有耐受性,此治疗方案值得应用推广。

Objective To explore in the postoperative recurrence or metastasis of gastric cancer treatment with S-1 capsule combined with paclitaxel in the treatment of clinical therapeutic effect. Methods Convenient selection selected in our hospi-tal in 2011-2015 admitted during the period of recurrence or metastasis of gastric cancer patients with 30 cases as the ob-ject of study, all patients were treated with S-1 capsule combined with paclitaxel treatment, and the treatment effect was observed and analyzed. Results After the combined treatment, patients with complete remission rate was 10.00%, partial re-mission rate of 43.33%; stable rate was 23.33% and disease progression rate was 23.33%, the total efficiency of the treat-ment was 53.33%, the adverse effects including gastrointestinal tract reaction, peripheral nerve toxicity, bone marrow sup-pression. Conclusion In recurrent or metastatic gastric cancer treatment given S-1 and paclitaxel combined with ideal treatment effect and adverse reaction of lighter, with tolerance, this treatment is worth popularization and application.