牙周非手术治疗对2型糖尿病伴慢性牙周炎患者血清中糖类及脂蛋白类物质的影响

Effect of non surgical periodontal therapy on serum carbohydrate and lipoproteins in patients with chronic periodontitis and type 2 diabetes mellitus

目的探讨牙周非手术治疗对2型糖尿病伴慢性牙周炎患者血清中糖类及脂蛋白类物质的影响。方法选取60例2型糖尿病伴慢性牙周炎患者,随机分成人数相等的治疗组和对照组,治疗组进行糖尿病常规治疗和牙周非手术治疗,对照组只进行糖尿病常规治疗,3个月后比较两组患者糖类及脂蛋白类物质的变化。结果治疗组牙周临床参数明显优于对照组(P<0.05)。治疗组Apo A1水平高于对照组,载脂蛋白A1、脂蛋白a水平低于对照组(P<0.05)。结论对2型糖尿病伴慢性牙周炎患者进行有效的牙周非手术治疗,可以显著改善患者牙周临床参数、血糖代谢和血清载脂蛋白A1、脂蛋白a水平,对患者的身体健康和生活质量有重要意义。

Objective To-investigate the effect of non surgical periodontal therapy on serum carbohydrate and lipoproteins in patients with chronic periodontitis and type 2 diabetes mellitus. Methods Sixty patients with type 2 diabetic patients and chronic periodontitis were randomly divided into treatment group and control. The treatment group received diabetic routine treatment and non-surgical periodontal treatment. The control group received only diabetic routine treatment. After three months, the carbohydrate and lipoproteins were examined and compared. Results The periodontal clinical parameters in the treatment group significantly improved compared with those in the control group （P 〈 0.05）. The level of ApoA1 was higher and HbA1 c and lipoproteins lower in the treatment group than those in the control （P 〈 0.05）. Conclusion The clinical periodontal parameters in patients with type 2 diabetes mellitus and chronic periodontitis could significantly improve by non-surgical periodontal therapy.