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血清CA125、经阴道B超检查及CT检查在子宫内膜癌术前评估方面的价值 被引量:17

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摘要 目的 探讨术前血清CA125、经阴道B超声检查(TVCDS)及CT检查在子宫内膜癌(EC)患者术前评估方面的价值。方法 回顾性分析76例确诊EC行分期手术的患者的临床资料,比较术前血清CA125、TVCDS及CT检查相联合,并与术后病理结果对比,分析各种检测手段在术前诊断EC在深肌层浸润(MI)、宫颈间质受累(CI)及盆腔淋巴结转移(PLNM)等方面的敏感性、特异性及准确性等指标。结果 (1)EC术前CA125阳性率Ⅰ期与Ⅱ~Ⅳ期差异有统计学意义(P〈0.01),在病理分级的阳性率之间差异无统计学意义(P〉0.05);(2)在诊断MI方面,与CT联合相比较,CA125联合TVCDS,其敏感性、特异性及准确性均高于前者,但差异均无统计学意义(P〉0.05);而当三者联合时,与CA125联合TVCDS相比较,其敏感性、特异性、准确性均有升高,但差异均无统计学意义(P〉0.05);(3)在诊断CI方面,与CA125联合TVCDS相比较,CA125联合CT,以及三者联合等两种方法,其敏感性、特异性及准确性均有所提高,但差异无统计学意义(P〉0.05)。(4)在诊断PLNM方面,与CA125相比,CA125联合CT检查,在敏感性、特异性及准确性均有所提升,其中特异性及准确性的提升,差异有统计学意义(P〈0.05)。结论 CA125及TVCDS在判断EC术前分期、病理分级、诊断MI、CI方面有较大的临床价值,但在诊断PLMN方面,CT更有优势。
作者 戴如星 明芳
出处 《重庆医学》 CAS 北大核心 2016年第24期3421-3424,共4页 Chongqing medicine
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参考文献19

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