内分泌腺来源的血管内皮生长因子在女性生殖中的研究进展被引量：7

Research progress of endocrine gland-derived vascular endothelial growth factor in female reproduction

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摘要内分泌腺来源的血管内皮生长因子(EG-VEGF)是近年研究发现的一种新的血管因子,其结构与VEGF不同而功能类似。作为迄今被发现的唯一的组织特异性血管生成因子,EG-VEGF在女性生殖系统中较VEGF有更为特异的功能,EG-VEGF在女性的月经周期、胚胎着床、妊娠维持等生殖功能中起重要作用,其功能亢进或不足与多种病理状态相关,但其作用机制尚未完全阐明。 Endocrine gland-derived vascular endothelial growth factor （EG-VEGF） is a new vascular factor, which has been discovered in recent years with different structure but similar function compared with VEGF. As the only tissue-specific angiogenic factor found so far, the function of EG-VEGF in female reproduc- tive system is more specific than that of VEGF. EG-VEGF plays an important role in female reproductive endo- crine system, including menstrual cycle, embryo implantation and pregnancy maintenance etc. Its hyperfunction or insufficiency is associated with a variety of pathological conditions. However, its mechanism has not been well elucidated.

作者姚丽华高敏芝

机构地区上海交通大学医学院附属仁济医院生殖医学中心

出处《生殖与避孕》 CAS CSCD 北大核心 2016年第8期660-665,共6页 Reproduction and Contraception

基金上海市自然科学基金项目资助,项目号:13ZR1424600

关键词内分泌腺来源的血管内皮生长因子(EG-VEGF) 生殖生理生殖病理血管发育 endocrine gland-derived vascular endothelial growth factor （EG-VEGF） reproductive physiology reproductive pathology vascular development

分类号 R339.22 [医药卫生—人体生理学]

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