摘要
内分泌腺来源的血管内皮生长因子(EG-VEGF)是近年研究发现的一种新的血管因子,其结构与VEGF不同而功能类似。作为迄今被发现的唯一的组织特异性血管生成因子,EG-VEGF在女性生殖系统中较VEGF有更为特异的功能,EG-VEGF在女性的月经周期、胚胎着床、妊娠维持等生殖功能中起重要作用,其功能亢进或不足与多种病理状态相关,但其作用机制尚未完全阐明。
Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) is a new vascular factor, which has been discovered in recent years with different structure but similar function compared with VEGF. As the only tissue-specific angiogenic factor found so far, the function of EG-VEGF in female reproduc- tive system is more specific than that of VEGF. EG-VEGF plays an important role in female reproductive endo- crine system, including menstrual cycle, embryo implantation and pregnancy maintenance etc. Its hyperfunction or insufficiency is associated with a variety of pathological conditions. However, its mechanism has not been well elucidated.
出处
《生殖与避孕》
CAS
CSCD
北大核心
2016年第8期660-665,共6页
Reproduction and Contraception
基金
上海市自然科学基金项目资助,项目号:13ZR1424600
关键词
内分泌腺来源的血管内皮生长因子(EG-VEGF)
生殖生理
生殖病理
血管发育
endocrine gland-derived vascular endothelial growth factor (EG-VEGF)
reproductive physiology
reproductive pathology
vascular development