摘要
目的研究三白草Saururus chinensis全草的化学成分。方法采用多种柱色谱法分离,通过理化鉴别及波谱分析技术鉴定化合物的结构。结果从三白草全草95%乙醇提取物中分离得到了7个化合物,分别鉴定为反式-7,8-二氢-7-（3,4-亚甲二氧基）苯基-1′-（2-氧丙基）-3′-甲氧基-8-甲基苯并呋喃（1）、4-（3-甲氧基-4-羟基）苯基-3-甲基-3-丁烯-2-酮（2）、（＋）-愈创木素（3）、（＋）-反式-1,2-二氢脱氢愈创木脂酸（4）、异落叶松脂素-4-O-β-D-葡萄糖苷（5）、异甘密树脂B（6）和perseal F（7）。结论化合物1为新化合物,命名为三白脂B,化合物2-7均为首次从该植物中分离得到。
Objective To study the chemical constituents in the whole plants of Saururus chinensis. Methods The chemical constituents were isolated by various column chromatographic methods. The structures of the compounds were elucidated on the basis of physiochemical properties and spectrascopic analysis. Results Seven compounds were obtained and identified as trans-7, 8-dihydro-7-（3,4-methylenedioxyl）-phenyl-1′-（2-oxopropyl）-3′-methoxy-8-methylbenzofuran（1）, 4-（3-methoxy-4-hydroxy） phenyl-3-methyl-3-buten-2-one（2）,（＋）-guaiacin（3）,（＋）-trans-1,2-dihydrodehydroguaiaretic acid（4）,（-）-isolariciresinol-4-O-β-D-glucoside（5）, isonectandrin B（6）, and perseal F（7）, respectively. Conclusion Compound 1 is a new compound named as saurusine B, and compounds 2—7 are obtained from this plant for the first time.
出处
《中草药》
CAS
CSCD
北大核心
2016年第13期2221-2225,共5页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金重点项目(30530860)
