母源性印记基因3抑癌作用机制的研究进展

Research on tumor suppressor mechanisms of maternally expressed gene 3

随着长链非编码RNA的研究热潮，母源性印记基因3（MEG3）作为长链非编码RNA家庭的一员也被广泛关注。MEG3不仅在良性疾病中有所研究，而且在恶性疾病中研究的更多且更为深入。MEG3因其抑癌的独特性在肿瘤研究中备受关注，但其抑癌的具体作用机制及相关途径还未完全明确，仍有待深入的研究与阐明。现本文将MEG3的抑癌作用及相关作用通路归纳总结。

As long non-coding RNA （LncRNA） research boom, Maternally Expressed Gene 3 （MEG3） as Ln- cRNA family is also a widespread concern. MEG3 not been studied in benign disease, and malignant disease more and more in-depth research. MEG3 because of the uniqueness of the tumor suppressor much attention in cancer re- search, but its specific mechanism of action of tumor suppressor and associated pathways have not been yet entirely clear, remains to be further research and clarify. This article will be now anticancer activity MEG3 and related Pathway summarized.