青岛市中老年双生子轻度认知功能障碍患病率的调查研究

The prevalence of mild cognitive impairment(MCI) in the middle and old age twins in Qingdao

目的调查青岛市中老年双生子轻度认知功能障碍(Mild Cognitive Impairment,MCI)的患病率。方法从青岛市双生子库中募集384对年龄≥40周岁的中老年双生子,其中同卵双生子244对,异卵双生子140对;用北京版蒙特利尔认知量表(Montreal Cognitive Assessment,MoCA)评估研究对象的认知功能状况。结果青岛市中老年双生子人群MCI的患病率是84.38%;同卵双生子的患病率是83.40%,异卵双生子的患病率是86.07%,不同卵型双生子MCI的患病率差异无统计学意义。不同年龄组MCI的发病率随年龄增长呈上升趋势。结论青岛市中老年双生子MCI患病率高,需要引起重视。

Objectives To investigate the prevalence of mild cognitive impairment（ MCI） in the middle and old age twins in Qingdao. Methods 384 twins more than 40-year old were collected from Qingdao twin library. There were 244 monozygotic twins and 140 fraternal twins. Beijing version of the Montreal Cognitive table Montreal Cognitive Assessment（ MoCA） was used to assess the cognitive function. Results The prevalence of MCI was 84.38% in the middle and old age twins in Qingdao. The prevalence of MCI was 83.40% in monozygotic twins and 86.07% in fraternal twins,which have no statistical differences. The prevalence of MCI in different age groups increased with age. Conclusions The prevalence of MCI is high,which need to be given more attention.