腹腔镜胃癌根治术患者围术期代谢指标及消化酶的变化研究

Change of metabolic indexes and digestive enzymes of laparoscopic radical gastrectomy for gastric cancer patients with perioperative

目的：探究腹腔镜胃癌根治术对患者围术期相关机体指标,包括代谢指标与消化酶相关指标的影响程度。方法：将本院2014年1月~2015年11月收治的70例胃癌患者按照随机数字量表法分为两组,对照组35例进行开腹根治术治疗,观察组35例进行腹腔镜根治术治疗,检测及比较两组术前及术后不同时间点的蛋白代谢及消化酶相关指标。结果：术前两组各检测指标差异均无统计学意义（P均〉0.05）,而术后1、3、7、14 d观察组蛋白代谢相关血清指标均高于对照组,消化酶相关指标也均优于对照组,差异均有统计学意义（P均〈0.05）。结论：腹腔镜根治术对胃癌患者围术期代谢指标及消化酶的影响波动相对更小,患者术后恢复相对较好。

Objective： To investigate the body related indexes of laparoscopic radical gastrectomy for gastric cancer patients with perioperative including metabolic indexes and digestive enzymes. Methods： A total of 70 patients with gastric cancer during January 2014 to November 2015 were divided into two groups by the method of random number table,35 patients with gastric cancer in control group were treated with open radical operation,35 patients with gastric cancer in observation group were treated with laparoscopic radical operation,then the preoperative and different postoperative time proteometabolism and digestive enzymes related indexes of two groups were detected and controlled. Results： The differences of detection result＇s statistical items of two groups before the operation were note obvious,all P〉0. 05,while the proteometabolism related indexes of observation group at first,third,seventh and fourteenth day after the operation were all higher than those of control group,the digestive enzymes related indexes were all better than those of control group too,all P〈0. 05. Conclusions： The fluctuation of laparoscopic radical operation for the metabolic indexes and digestive enzymes of patients during the perioperative period are relatively smaller,and the postoperative recovery of patients is more.