艾滋病患者终止抗病毒治疗后的生存状况分析

Analysis of Living Condition of Aids Patients after Stopping the Antivirus Treatment

目的对艾滋病患者终止抗病毒治疗后的生存状况进行探讨。方法选取该院2011年7月—2013年7月共收治的60例艾滋病患者,回顾性分析其临床资料。结果男性比例高于女性,传播的途径以性传播为主;终止病毒治疗后第12、24、36、48个月,累计生存率分别为0.85、0.78、0.74、0.65;多因素COX回归分析后发现,患者的生存时间与性别、年龄、感染途径、最近一次的CD4淋巴细胞计数水平、终止治疗时有无治疗药物毒副作用,密切相关。结论终止抗病毒治疗会使患者生存时间减少,应加强患者的治疗依从性,减少停药情况的发生,最大限度地延长患者生存时间。

Objective To study the living condition of aids patients after stopping the antivirus treatment. Methods 60 cases of aids patients admitted and treated in our hospital from July 2011 to July 2013 were randomly selected and the clinical data of them were retrospectively analyzed. Results The male proportion was higher than the male proportion, and sexual transmission was the main way, the cumulative living rates were respectively 0.85,0.78,0.74,0.65 in 12,24,36,48 months after stopping the antivirus treatment; the multi-factor COX regression analysis showed that the living time of patients was closely related to the gender, age, infection way, latest CD4 lymphocyte count level and whether there was the toxic side effects of treatment drugs at the time of stopping treatment. Conclusion Stopping the antivirus treatment can reduce the living time of patients, and we should enhance the treatment compliance of patients, reduce the occurrence of drug withdrawal and maximize the living time of patients.