仿耻骨直肠肌式人工肛门括约肌系统

Mechanical bionicartificial anal sphincter system

目的国内外一直在探寻肛肠的奥秘以及救助肛门失禁病患的办法,开展了许多人工肛门括约肌系统的研究。本文设计了一种仿耻骨直肠肌式的新型人工肛门括约肌系统,以解决现有人工肛门括约肌系统存在的血供不足、无"便意"感知以及没有安全且稳定的能量供给等问题。方法系统主要功能为通过自制压力传感模块提取肠道周围压力信息,传递至微型处理器,最终控制括约肌执行结构实现排便操作。其关键技术包括括约肌执行机构内侧嵌入超薄自制生物压力传感器实时感知肠道压力变化,根据此压力参数,系统智能识别便意并实现排便预警。系统采用仿人体机制的运作方式并且结合血供压力的采集模块,能有效避免出现局部高压导致肠道缺血性坏死。系统采用无线能量传输方式提供能量实现安全供能。结果采用淀粉糊状物以及水来验证括约肌执行结构对糊状以及液态粪便的夹持效果,结果表明夹持状况良好。通过体外肠道动物实验得到了模拟肠道周围的压力信号与"便意"产生的关系,验证了系统能够在排便阈值达到以后实现报警,进而提醒患者进行排便操作。实验表明,通过使用无线供能的方式以及低功耗处理,可使系统每次充电后工作6.2天。结论通过实验验证表明系统可有效控制排泄物,并成功建立排便感知信号,实现智能控便。

Objective The anorectal mystery and ways to rescue the anal incontinence patients are explored to solve the anal incontinence problem. This paper designs a new artificial anal sphincter system as an imitation of puborectalis muscle type. Methods In this system, an imitation of puborectalis muscle type of artificial anal sphincter is devised, with several embed biological pressure sensors to percieve the pressure of intestinal canal. According to the pressure parameter, the system could intelligently recognize the awareness of the defecation and offer an alarm to the patient. The system adopts bionic principle and combines with blood pressure acquisition module to effectively avoid the partial high pressure leading to intestinal isehemic necrosis. And the transcutaneous energy transmission is adopted to provide the energy in a biosafety way. Results Starch paste and water are used to verify the paste and liquid manure clamping effect of sphincter implementation structure and the results show that holding is in good condition. Through isolated intestinal animal experiment, we can see the relationship between the simulated intestinal pressure signals and ＇means＇ , and verify that the system can realize alarm after defecation threshold is reached and remind the patient to carry out operation of defecation. The system can work 6.2 d after every charging with a wireless energy supply way and a low power consumption. Conclusions The results of in vitro experiments indicate that the system can control the facel and rebuild the defecation successfully.