结直肠癌肝转移分子机制的研究新进展

New research progress in molecular mechanisms of colorectal liver metastasis

结直肠癌是最常见的恶性肿瘤之一，其致死率很高。大约1／3的结直肠癌患者发生同时性或异时性肝转移，而且发生肝转移的患者预后一般较差，因此研究结直肠癌肝转移的机制非常重要。近年来关于结直肠癌肝转移分子机制的研究越来越多，本文主要对其中一些分子机制的研究进行归纳总结，希望能对结直肠癌肝转移患者的诊治和预防提供新思路。

Colorectal cancer is one of the most common malignant tumor with high mortality rate. About a third of patients with colorectal cancer have either simultaneously or metachronous liver metastasis with poor prognosis. Therefore, the studies on the mechanisms of colorectal liver metastasis is significant. Recently, the research on the molecular mechanisms of colorectal liver metastasis is increasing, this paper summarizes some of them, and we hope providing new ideas for the diagnosis and treatment of colorectal cancer patients with liver metastasis.