血浆雌二醇水平与新疆维吾尔族男性TAO易感性的关系

Relation on the serum estradiol levels and the susceptibility to throm- boangitis obliteransin in a population of Uyghur nationality male from Xinjiang

目的探讨血浆雌二醇水平与新疆维吾尔族男性血栓闭塞性脉管炎易感性的关系。方法采用多级、整群抽样的方法随机抽取新疆喀什地区健康维吾尔族男性500名，查阅新疆维吾尔自治区人民医院体检的健康汉族男性人群的资料，随机抽取300名，分别检测血浆雌二醇，对比分析两种族间雌二醇水平差异有元统计学意义。结果维吾尔族男性血浆雌二醇水平平均为（31．49±12．55）μg／ml，汉族人群平均为（26．68±12．40）μg／ml，单因素分析得出，不同民族间雌二醇水平的差异具有统计学意义（t=5．267，P〈0．05），且维吾尔族人群的血浆雌二醇水平明显高于汉族，而是否吸烟及不同年龄组人群的雌二醇水平比较，差异无统计学意义（t=0．346，F=1．820，P〉0．05）；多因素回归分析显示，仅有民族对雌二醇水平的影响具有统计学意义（P〈0．05）。结论新疆维吾尔族健康男性人群血浆雌二醇水平较汉族男性高，血浆雌二醇水平较高可能是维吾尔族男性血栓闭塞性脉管炎的易感性因素之一。

Objective To evaluate the relationship between the serum estradiol levels and susceptibility to thrombo- angitis obliterans（TAO） in a population of Uighurs from Xinjiang. Methods Clinical data were concluded 500 Uighur healthy male through the method of multistage and cluster sampling randomly in Xinjiang Kashi area, 300 cases of Hans male came from the healthy physical examination in Xinjiang Uygurs Autonomous Region Pepole＇s Hospital, examining the serum estradiol levels and analysising whether had the statistical significance between Uygurs and Hans nationality. Results The estradiol levels of Uighur male was （31.49 ±12.55） pg/ml, the hans was （26.68 ±12.40） pg/ml,single factor analysis, the difference with plasma estradiol levels have statistical significance between ethnic groups （t = 5. 267, P 〈 0.05 ）, and serum estradiol levels of uygur people was higher than Hans, and the estradiol levels with different smok- ers and age groups,there was no statistically signifieant difference （ t = 0. 346, F = 1. 820, P 〉 0.05）. Logistic regression analysis indicated that only ethnic difference have statistically significant influence on estradiol levels （ P 〈 0. 05 ）. Conclusions The serum estradiol levels of Uighur healthy male in Xinjiang are higher than Hans. The high serum estradiol levels may be a susceptible factor of thromboangitis obliterans to Xinjiang Uygur.