针吸细胞块技术在术前乳腺癌分子分型诊断中的应用及发展

Application and development of FNA cell block on preoperative breast cancer molecular typing

分子分型是乳腺癌个体化治疗的基础，免疫组化表型反映乳腺癌的分子分型，穿刺活检是术前乳腺癌分子分型诊断的主要方法。随着细针针吸细胞学技术的创新与发展，可以运用针吸细胞块技术进行术前乳腺癌分子分型检查。针吸细胞块基础上明确乳腺癌的分子亚型及生物学特征，为临床制订合理的个体化治疗方案提供病理依据，具有重要的临床意义。

Fine needle aspiration cytopathology of the breast is an effective means of distinguishing malignant from benign, and the aspirated sample collections techniques is the primary and key part of fine needle aspiration. Fine needle aspiration cell block has been improved and used on preoperative breast cancer molecular portraits. This paper will provide an introduction to application of specimens collection techniques, application and development of fine needle aspiration cell block on preoperative breast cancer molecular portraits.