CPAP结合咖啡因治疗早产儿频发呼吸暂停的临床效果分析

Efficacy of Citrated Caffeine Versus CPAP for Apnea of Prematurity

目的为了提高治疗早产儿频发呼吸暂停的效果并减少各种不良事件发生的情况,探讨和研究给予持续气道正压通气(CPAP)呼吸机联合咖啡因治疗的价值和意义。方法按照随机原则抽取68例于2015年3月—2016年3月来该院治疗的早产儿频发呼吸暂停患者作为研究对象并通过抽签的方法方法将其分为试验组和对照组各34例,入组所有患者均给予咖啡因治疗,而试验组患儿同时给予CPAP呼吸机治疗,比较不同治疗方案的疗效差异。结果经过对比研究发现,对照组患者总有效率24(70.59%)明显低于对照组患者的总有效率30(88.24%),且两组比较差异具有统计学意义(P<0.05)。结论持续气道正压通气(CPAP)呼吸机联合咖啡因治疗早产儿频发呼吸暂停,不仅能够明显的提高临床的治疗效果,预防和减少各种不良事件的发生率,疗效确切,值得推荐和应用。

Objective To study and analyze the efficacy of citrated caffeine versus CPAP for Apnea of prematurity in the process of treatment, in order to improve the treatment advantage and effectively prevent and reduce the incidence of adverse events of infantile pneumonia in our hospital.Methods 68 cases with Apnea of prematurity of hospitalized patients,which admitted in our hospital for surgical treatment during March 2015 – March 2016, were selected as the research object according to random number table method and were divided into experimental group and control group in draw lots method（in each group, n=34）. All patients were given the caffeine citrate, and experimental group were given citrated caffeine versus CPAP at the same time. The effects were compared. Results After research data analysis found that the total effective rate of the observation group was 30（88.24%） and that of the control group was 24（70.59%）,the clinical curative effect of the observation group was more significant. Symptoms improved of the observation group was better than that of the control group, the difference was significant statistically significant（P〈0.05）. Conclusion Citrated caffeine versus CPAP for Apnea of prematurity in the process of treatment can not only obviously improve the clinical therapeutic effect, but also prevent and reduce the incidence of various complications, which has exact curative effect and worthy recommend and application.