有创机械通气治疗ICU重症心力衰竭的可行性研究

Invasive Mechanical Ventilation Feasibility Study for the Treatment of Severe Heart Failure in the ICU

目的研究有创机械通气治疗ICU重症心力衰竭的可行性。方法研究资料方便选取2014年1月—2016年2月该院ICU重症心力衰竭患者68例,根据随机数字法,分为2组,保守+有创通气组和保守组。保守组采取常规疗法;保守+有创通气组在保守组基础上增加有创机械通气治疗。就两组患者治疗前后血氧饱和度、左室射血分数、心率、呼吸、抢救有效率进行比较。结果保守+有创通气组抢救有效率88.24%高于保守组67.65%,χ2检验显示P<0.05。治疗前两组患者血氧饱和度、左室射血分数、心率、呼吸差异无统计学意义,保守+有创通气组为(70.12±4.56)%、(38.53±0.35)%、(125.12±9.56)次/min、(35.12±4.56)次/min,保守组为(70.34±5.35)%、(36.94±0.36)%、124.34±9.35)次/min、(35.34±5.35)次/min,t检验显示P>0.05。治疗后保守+有创通气组患者心率、呼吸、血氧饱和度、左室射血分数优于保守组,保守+有创通气组为(94.75±5.36)%、(48.61±0.26)%、(86.75±7.36)次/min、(20.75±3.36)次/min,保守组为(89.62±5.03)%、(43.18±0.37)%、(98.62±9.03)次/min、(29.62±5.03)次/min,t检验显示P<0.05。结论有创机械通气治疗ICU重症心力衰竭的可行性高,可有效改善患者血气指标和心功能,改善患者预后,值得推广。

Objective To study the invasive mechanical ventilation feasibility for the treatment of severe heart failure in the ICU. Methods The data from January 2014-February 2014, our hospital ICU patients with severe heart failure in 68 cases, according to the method, the coin toss is divided into two groups, conservative ＋ invasive ventilation and conservative groups. Conservative groups adopt conventional therapy; Conservative ＋ invasive ventilation in the conservative group on the basis of increasing invasive mechanical ventilation treatment. Two groups before and after treatment in patients with heart rate, breathing, and blood oxygen saturation, left ventricular ejection fraction, comparing rescue efficiency. Results Conservative ＋ invasive ventilation group was 88.24% higher than the conservative group 67.65%, χ^2test showed that P〈0.05.Before treatment, there was no significant difference in blood oxygen saturation, left ventricular ejection fraction, heart rate and respiration rate between the two groups.（70.12±4.56）%,（38.53 ±0.35）%,（125.12±9.56）times/min,（35.12±4.56）times/min, the conservative group is（70.34 ± 5.35）%,（36.94±0.36）%,（124.34 ± 9.35）times/min,（35.34±5.35）times/min, t test showed that P〉0.05. After treatment, conservative ＋ has a ventilation groups in heart rate, respiration, blood oxygen saturation, left ventricular ejection fraction（LVEF） is superior to conservative group, the conservative ＋ with invasive ventilation group for（94.75 ±5.36）%,（48.61 ±0.26）% and（86.75 ±7.36） times/min,（20.75 ±3.36） times/min, conservative group for（89.62±5.03）% and（43.18±0.37）%,（98.62±8.03） times/min,（29.62±5.03） times/min, the t-test showed P〈0.05. Conclusion The invasive mechanical ventilation for the treatment of severe heart failure in the ICU feasibility is high, can effectively improve the patients＇ blood gas index and cardiac function, improve the prognosis of patients, is worth promoting.