翼状胬肉切除术后配戴角膜绷带镜的疗效分析

Analysis of efficacy of corneal bandage lens after pterygium resection

目的评估角膜绷带镜应用于胬肉切除联合自体角膜缘干细胞移植术的有效性。方法选取翼状胬肉患者58例(62眼),行胬肉切除联合自体角膜缘干细胞移植术,随机分为两组,实验组(共29例31眼)术后第1天开始佩戴角膜绷带镜,对照组(共29例31眼)行常规眼垫包扎治疗,观察两组术后1 d、4 d、7 d及1个月时眼部症状及术后9个月时的恢复情况。结果术后第1天、第4天,两组患者眼部症状评分差异具有统计学意义(P<0.05);术后第7天、第1个月差异无统计学意义(P>0.05),时间因素与分组因素之间有交互作用(P<0.05);术后9个月,两组复发率差异无统计学意义(P>0.05)。结论胬肉术后佩戴角膜绷带镜对降低胬肉术后复发率无明显影响,但可减轻角膜不适反应,提高患者舒适度,是一种简单有效、适宜推广的辅助治疗措施。

Objective To evaluate the effectiveness of corneal bandage lens after pterygium resection combined with autologous limbal stem cell implantation. Methods A total of 58 patients（ 62 eyes） with pterygium were selected and given pterygium resection combined with autologous limbal stem cell implantation. They were randomly divided into experimental group and control group,29 patients（ 31 eyes） for each group. Experimental group was given corneal bandage lens on postoperative d1,while control group was treated with routine eye pad dressing. Eye conditions 1 d,4 d,7 d and 1 month after operation and recovery condition 9 months after operation were observed in both groups. Results There were significant differences betw een two groups in eye condition scales 1 d and 4 d after operation（ P〈0. 05）,but the differences were not significant 7 d and 1 month after operation（ P〉0. 05）. There was interaction betw een time and grouping factors（ P〈0. 05）. And 9 month after operation,there was no significant difference betw een two groups in recurrence rate（ P〉0. 05）. Conclusion Application of corneal bandage lens after pterygium resection has no significant influence on postoperative recurrence rate of pterygium,but can relieve the corneal discomfort,and increase patients＇ comfort,so it is an simple,effective and suitable complementary therapeutic method deserving to be popularized.