关于核磁诊断区分阿尔茨海默病和血管性痴呆的临床价值探讨

Clinical Value of Distinguishing between Alzheimer's Disease and Vascular Dementia with Nuclear Magnetic Resonance

目的：探讨采用核磁诊断区分阿尔茨海默病和血管性痴呆的临床价值。方法：选取某院2012年9月-2015年8月收治的痴呆患者60例,根据治疗目的不同,分为A、B两组,A组为AD患者,B组为VD患者,同时选取30例健康患者为C组,采用MRI进行扫描并对其数据进行分析。结果：A组海马体积明显小于B、C两组（P〈0.05）;B、C两组海马体积相比无明显差异（P〉0.05）。A组的颞叶沟回间距明显高于B、C两组（P〈0.05）。A组大脑萎缩26例,B组19例,A组大脑萎缩发生率明显多于B组（P〈0.05）。A组海马萎缩18例,B组10例,A组海马萎缩发生率明显多于B组（P〈0.05）。结论：MRI是一种无创的检查方法,能够从影象学角度活体区分AD、VD,具有重要临床意义。

Objective To investigate the clinical value of distinguishing between Alzheimer＇s disease and vascular dementia with nuclear magnetic resonance. Methods： 60 cases of patients with vascular dementia in a hospital from September 2012 to August 2015 were divided into three groups according to different treatment purposes,the A group were AD patients,B group were VD patients, and 30 healthy patients were in C group, use MRI to scan and analyze the data.Results： The hippocampal volume of A group was significantly smaller than that of B and C group（P 〈0.05） ; there was no significant difference between B and C group （P 〉0.05） The distance between the temporal lobe of the A group was significantly higher than that in the B and C group（P〈0.05）.The brain atrophy in A group was 26 group was 19, and A group was significantly higher than that in B group （P 〈0.05 ）.Hippocampus atrophy in A group was 18, B group was 10 , the incidence of hippocampal atrophy in group A was significantly more than that in B group（P 〈0.05）. Conclusion ： MRI is a noninvasive method,which can distinguish AD and VD from the aspect of imageology, and it has important clinical significance.