血液透析治疗重症急性胰腺炎临床应用效果评价及分析

Evaluation and Analysis of Clinical Effect of Hemodialysis in the Treatment of Severe Acute Pancreatitis

目的:研究血液透析(HD)治疗重症急性胰腺炎(SAP)的疗效。方法:62例SAP患者根据治疗方式分为两组:31例常规内科治疗为对照组,另31例内科治疗联合HD治疗为观察组,对比两组的临床预后。结果:观察组的临床治愈率为93.55%,显著高于对照组的74.19%(P<0.05);观察组的腹胀、腹痛、腹膜刺激征消失时间及住院时间均较对照组显著缩短(P<0.05);治疗后观察组的ALT、AST、Scr、IL-6、TNF-α及CRP均显著低于治疗前及对照组(P<0.05)。结论:HD治疗SAP能够促进炎症因子的清除,改善和稳定血液内环境,促进病情康复,降低SAP死亡率,改善临床预后,值得推广应用。

Objective To study the effect of hemodialysis （HD） in the treatment of severe acute pancreatitis （SAP）. Methods： 62 patients with SAP were divided into two groups according to the treatment method： 31 cases in the control group were treated with conventional treatment in the Department of internal medicine, the other 31 cases in the observation group were treated with internal treatment with HD, and the clinical prognosis of the two groups were compared. Results： The clinical cure rate of the observation group was 74.19% , significantly higher than that of the control group （P〈0.05）. The observation group was significantly shorter than the control group （P〈0.05）. The ALT, Scr, IL-6 , TNF-α, AST and CRP were significantly lower than those in the control group （P〈0.05）. Conclusion： HD treatment of SAP can promote the removal of inflammatory factors, improve and stabilize blood environment, promote the rehabilitation of patients, reduce SAP mortality,improve clinical prognosis, which is worthy of popularization and application.