胃溃疡应用阿莫西林辅以不同质子泵抑制剂的疗效比照

Efficacy of Amoxicillin and Different Proton Pump Inhibitors in the Treatment of Gastric Ulcer

目的:评析胃溃疡应用阿莫西林辅以不同质子泵抑制剂(奥美拉唑与泮托拉唑)治疗的临床效果。方法:112例胃溃疡患者根据质子泵抑制剂应用的不同分为对照组56例与实验组56例,前者予以奥美拉唑联合阿莫西林治疗,后者予以泮托拉唑联合阿莫西林治疗。结果:实验组患者的用药后临床总有效率高达94.6%,较之总有效率为75.0%的对照组更具优越性。结论:作为第三代质子泵抑制剂的泮托拉唑辅以阿莫西林治疗胃溃疡,在临床疗效与跟踪随访复发情况上较第一代质子泵抑制剂的奥美拉唑辅以阿莫西林均有明显优势,可作为首选口服用药方案在临床推广与应用。

Objective To analyze the clinical effect of the treatment of gastric ulcer with amoxicillin com-bined with different proton pump inhibitors （omeprazole and pantoprazole）. Methods： 112 cases of gastric ulcer patients according to the different use of proton pump inhibitors for the control group （56 cases） and experimental group （56 cases） , the former treated with omeprazole combined with amoxicillin, the latter to be combined with pantoprazole amoxicillin therapy. Results： The clinical total effective rate of the experimental group was 94.6% , and the total effective rate was Conclusion： As the third generation of proton pumpinhibitor pantoprazole combined with amoxicillin in the treatment of gastric ulcer, in clinical efficacy and follow-up recurrence,it has advantages over the first generation of proton pump inhibitors combined with omeprazole, which can be used as the preferred oral regimen in clinical promotion and application.