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角膜缘干细胞移植术联合角膜绷带镜治疗翼状胬肉 被引量:8

Corneal Limbal Stem Cell Transplantation Combined with Corneal Bandage Lens in the Treatment of Pterygium
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摘要 目的:评价角膜绷带镜在翼状胬肉切除联合角膜缘干细胞移植术后对角膜修复的作用。方法将60例患者随机分配至观察组与对照组,两组均行翼状胬肉切除联合角膜缘干细胞移植术。术后,观察组立即佩戴角膜绷带镜,对照组常规包扎术眼。两组均用妥布霉素地塞米松眼液、重组人上皮细胞生长因子眼液点眼。观察两组角膜上皮修复情况及角膜刺激症状。结果术后观察组角膜上皮修复时间(3.33±0.99)d较对照组(4.80±1.00)d明显缩短,差异有统计学意义(P=0.000);术后1-5d观察组眼部舒适度评分明显优于对照组,差异有统计学意义(P〈0.05)。结论翼状胬肉切除联合角膜缘干细胞移植术后使用角膜绷带镜可促进角膜创面修复,减轻角膜刺激症状。 Objective To evaluate the effect of corneal bandage lens on corneal repair after pterygium excision combined with corneal limbal stem cell transplantation. Methods 60 cases were randomly allocated to the observation group and the control group, and two groups were both treated with pterygium excision combined with corneal limbal stem cell transplantation. After the operation, the observation group immediately wore corneal bandage lens, while the control group received routine dressing. Two groups were treated with tobramycin and dexamethasone eye drops, recombinant human epidermal growth factor eye drops. Corneal epithelial repair and corneal irritation symptoms of the two groups were observed. Results The time of corneal epithelial repair (3. 33±0. 99) d in the observation group was significantly shorter than that in the control group (4. 80 ± 1) d (P=0. 000). After 1d to 5d of operation, the eye comfort rating marks of the observation group was significantly better than that of the control group. Conclusion Excision of pterygium combined with corneal limbal stem cell transplantation can promote corneal wound repair and reduce corneal irritation.
出处 《四川医学》 CAS 2016年第8期860-862,共3页 Sichuan Medical Journal
基金 西藏自治区科技厅科技项目(编号:Z2014A08G2-2)
关键词 角膜缘干细胞移植术 角膜绷带镜 翼状胬肉 治疗 corneal limbal stem cell transplantation corneal bandage lens pterygium treatment
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