依达拉奉治疗脑梗死38例临床观察

Clinical Analysis Edaravone Treatment of Cerebral Thrombosis for 38 Cases

目的观察依达拉奉治疗脑梗死的临床效果。方法选择2013年5月—2015年5月收治的75例脑梗死患者的临床资料,随机分为观察组(n=38)与对照组(n=37),所有患者均给予常规溶栓、抗凝、抗血小板聚集、降血压等对症治疗。对照组在常规治疗的基础上,给予静脉滴注胞二磷胆碱;观察组在常规治疗的基础上,给予静脉滴注依达拉奉。结果治疗后7 d与14 d,两组患者神经功能缺损改善情况比较具有显著性差异(P<0.05);治疗14 d,两组患者有效率比较,具有显著性差异(P<0.05)。结论依达拉奉可有效改善脑血栓形成梗死患者神经功能缺损症状,具有一定临床应用价值。

Objective To observe the edaravone clinical efficacy of the treatment of cerebral throm-bosis. Methods From May 2013 to May 2015 clinical data of 75 cases of patients with cerebral throm-bosis was selected, according to the principle of random selection of figures, and the patients were divided into treatment group （n = 3 8） and control group （n =37） . All patients were given the same thrombolytic ,anticoagulant, anti-platelet aggregation, lowering blood pressure, lowering blood sugar, anti-infection treatment, the control group of patients on conventional treatment, were given intravenous infusion of citicoline treatment on the basis of conventional therapy, intravenous infusion edaravone. Clinical efficacy of the two groups of patients were compared. Results Before treatment, patients neurological deficit had no significant difference （P 〉0. 05） , but the first 7 d and 14 d, two neurologic impairment condition improved after treatment. The result was a significant difference （P 〈0. 05）. Treatment effect observed after treatment, the two groups were relatively efficient, the result was a significant difference （P 〈0. 05）. Conclusion Edaravone can improve cerebral thrombosis in patients with symptoms of neurological deficit and is worth of clinical application.