四维应变成像评价2型糖尿病患者早期左室收缩功能

Four dimensional strain imaging evaluation of early left ventricular systolic function in patients with type 2 diabetes

目的:应用四维应变成像技术评价左室构型尚未改变时的2型糖尿病患者左心室整体应变与节段应变功能,及早发现糖尿病患者左室收缩功能异常,为临床治疗提供依据。方法:选取同时段糖尿病组与对照组各45例,应用四维应变成像技术检测,自动生成左室收缩功能参数:1常规参数:左室舒张末期容积(EDV)、收缩末期容积(ESV)、心搏量(SV)、心输出量(CO)、射血分数(EF)、球形指数(Spl);2整体应变参数:左室整体纵向应变(LVGLS)、左室整体径向应变(LVGRS)、左室整体面积应变(LVGAS)、左室整体圆周应变(LVGCS);3节段应变参数:选取左室节段纵向应变(LVRLS)、左室节段面积应变(LVRAS)等。将两组各参数进行比较分析。结果:1左室收缩功能常规参数:EDV、ESV、SV、CO、EF、Spl两组比较差异,均无统计学意义(P>0.05)。2左室整体应变参数:LVGLS、LVGRS、LVGAS、LVGCS两组比较差异,有统计学意义。3左室节段应变:LVRLS、LVRAS,两组比较差异,有统计学意义。LVRLS以基底段的前、后间隔壁,中间段的后间隔壁、下壁,心尖段的间隔壁与下壁最为明显;LVRAS以基底段的后间隔壁、中间段的前、后间隔壁、下壁最为明显。结论:四维应变成像评价2型糖尿病患者早期左室收缩功能有较高价值,可为临床治疗方案提供依据。

Objective：We applied four dimensional strain imaging to evaluate left ventricular segmental integral strain and strain function of type 2diabetes＇ patients whose left ventricular configuration had not been changed.Method：We selected 45 samples of synchronous DM groups and the control groups,and applied four dimensional strain imaging to detect left ventricular systolic function parameters which were automatic generated,then compared each parameters of two groups.Result：1Normal left ventricular systolic function parameters,EDV,ESV,SV,CO,EF and Spl were similar between the two groups,and there were no statistical significance（P〉 0.05）.2Left ventricular strain parameters：LVGLS,LVGRS,LVGAS and LVGCS in the two groups were statistically significant（P〈 0.05）,and the significant in LVGLS was more apparent.3LVRLS and LVRAS in the two groups had statistical significance（P 〈0.05）.And it was most obvious in LVRLS that the front and back wall in basal segment,the back and below wall in the middle segment,interval and below wall in apex section;And it was most obvious in LVRAS that the back wall in basal segment,the front and back interval wall as well as inferior wall in the middle segment.Conclusion：Four dimensional strain imaging has a high diagnostic value to evaluate the early abnormal systolic function of left ventricular in patients with type 2diabetes.