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维汉抑郁症患者治疗前后视觉事件相关电位P300的对比研究

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摘要 目的比较维汉抑郁症患者视觉事件相关电位(ERP)在治疗前后的改变特征.方法对52例维族和50例汉族患者符合《国际疾病分类》第10版(ICD-10)中“抑郁发作”诊断标准的抑郁症患者在抗抑郁药物治疗前后均经汉密顿抑郁量表(HAMD)及BrainMaster脑诱发电位系统完成视觉P300检测.结果①维汉患者治疗后P300潜伏期和波幅较治疗前潜伏期明显缩短且波幅增高(P〈0.01)有显著性统计学差异.维汉患者治疗后HAMD评分较治疗前有显著性统计学差异(P〈0.01).②维汉患者治疗前后比较无统计学差异(P〉0.05).结论P300可作为评价维汉抑郁症治疗效果和对认知功能损害评定的-个客观的电生理学指标.
出处 《中华临床医师杂志(电子版)》 CAS 2016年第11期100-100,共1页 Chinese Journal of Clinicians(Electronic Edition)
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