期刊文献+

急性ST段抬高型心肌梗死患者心电图3级缺血的易患因素及预后价值 被引量:12

原文传递
导出
摘要 目的 评估心电图3级缺血(G3I)对急性ST段抬高型心肌梗死(STEMI)患者直接经皮冠状动脉介入治疗(pP-CI)术后预后的影响,探讨G3I的易患因素并识别其高危人群,以有效干预来改善临床结果.方法 入选接受pPCI的STEMI患者318例,按入院时心电图缺血分级分成G2I组和G3I组,术后随访12个月,记录患者院内和出院后的主要心血管不良事件.结果 G3I组的患者年龄大,起病-就诊时间长,梗死前心绞痛发生率、左室射血分数、ST段回落率低,TIMI危险积分、阿昔单抗和装置降低晚期血管成形术并发症的对照(CADILLAC)危险积分高,血清NT-proBNP、肌钙蛋白I峰值、CK-MB峰值高,SPECT提示的梗死面积大,两组间Killip分级差异有统计学意义(P均<0.05).G3I组患者pPCI术后的住院时间长,总的主要心脏不良事件发生率高(P<0.05).多变量分析提示,梗死前心绞痛缺如、起病-就诊时间>6h、TIMI危险积分>3分、CADILLAC危险积分>7分、前壁心肌梗死、Killip分级>Ⅰ级是STEMI患者入院时G3I的预测因子.结论 梗死前心绞痛缺如、起病-就诊时间>6h、TIMI危险积分>3分、CADILLAC危险积分>7分、前壁心肌梗死、Killip分级>Ⅰ级对G3I有良好的预测能力;入院时ECG上出现G3I的STEMI患者pPCI术后具有更差的临床结果.
出处 《中国医师杂志》 CAS 2016年第8期1223-1226,共4页 Journal of Chinese Physician
  • 相关文献

参考文献15

  • 1de LemosJA, BraunwaldE. ST segment resolution as a tool for assessing the efficacy of reperfusion therapy. J Am Coll Cardiol, 2001, 38 (5) :1283-1294. DOI:10.1016/S0735-1097(01)01550-9.
  • 2BridleBR, StuckeyTD, HansenC, et al. Relation between electrocardiographic ST-segment resolution and early and late outcomes after primary percutaneous coronary intervention for acute myocardial infarction. Am J Cardiol, 2005, 95(3): 345-348. DOI: 10.1016/j.amjcard.2004.09.031.
  • 3彭彬,夏豪.急性心肌梗死再灌注治疗后ST段回落的研究进展[J].心血管病学进展,2010,31(5):718-722. 被引量:8
  • 4BirnbaumY, HerzI, SclarovskyS, et al. Prognostic significance of the admission electrocardiogram in acute myocardial infarction. J Am Coll Cardiol, 1996, 27(5): 1128-1132.DOI:10.1016/0735-1097(96)00003-4.
  • 5SyedMA, BorzakS, AsfourA, et al. Single lead ST-segment recovery: a simple, reliable measure of successful fibrinolysis after acute myocardial infarction. Am Heart J, 2004, 147(2):275-280. DOI: 10.1016/j.ahj.2003.08.010.
  • 6AntmanEM, CohenM, BerninkPJ, et al. The TIMI risk score for unstable angina/non-ST elevation MI: A method for prognostication and therapeutic decision making.JAMA, 2000, 284(7): 835-842. DOI:10.1001/jama.284.7.835.
  • 7HalkinA, SinghM, NikolskyE, et al. Prediction of mortality after primary percutaneous coronary intervention for acute myocardial infarction: the CADILLAC risk score. J Am Coll Cardiol, 2005, 45(9):1397-1405.DOI: 10.1016/j.jacc.2005.01.041.
  • 8BirnbaumGD, BirnbaumI, BirnbaumY. Twenty years of ECG grading of the severity of ischemia.J Electrocardiol, 2014, 47(4):546-555. DOI: 0.1016/j.jelectrocard.2014.02.003.
  • 9BirnbaumY, SclarovskyS. The grades of ischemia on the presenting electrocardiogram of patients with ST elevation acute myocardial infarction. J Electrocardiol, 2001, 34Suppl:17-26. DOI: 10.1054/jelc.2001.28819.
  • 10KurtM, KarakasMF, BuyukkayaE, et al. Relation of angiographic thrombus burden with electrocardiographic grade3 ischemia in patients with ST-segment elevation myocardial infarction. Clin Appl Thromb Hemost, 2014, 20(1):31-36. DOI: 10.1177/1076029613476340.

二级参考文献50

  • 1Antman EM,Anbe DT,Armstrong PW,et al.ACC/AHA guidelines for the management of patients with ST elevation myocardial infarction[J].Circulation,2004,110(9):588-636.
  • 2Schr(o)der K,Wegscheider K,ZeymerU,et al.Extent of ST-segment deviation in the single lead of maximum deviation present 90 or 180 minutes after start of thrombolytic therapy best predicts outcome in acute myocardial infarction[J].Z Kardiol,2001,90(8):557-567.
  • 3Schr(o)der R,Wegscheider K,Schrder K,et al.Extent of early ST-segment resolution:a strong predictor of outcome in patients with acute myocardial infarction and a sensitive measure to compare thrombolytic regimens[J].J Am Coll Cardiol,1995,26(7):1657-1664.
  • 4Anderson RD,White HD,Ohman EM,et al.Predicting outcome after thrombolysis in acute myocardial infarction according to ST-segment resolution at 90 minutes:a substudy of the GUSTO-Ⅲ trial[J].Am Heart J,2002,144(1):81-88.
  • 5Schr(o)der R,Zeymer U,Wegscheider K,et al.Comparision of the prective value of ST segment elevation resolution at 90 and 180 min after start of streptokinase in acute myocardial infarction:a Substudy of the Hirudin for Improve of Thrombolysis(HIT)-4 study[J].Eur Heart J,1999,20(21):1563-1571.
  • 6Fu Y,Goodmma S,Chang WC,et al.Time to treatment influence the impact ST segment resolution on one-year:insight from the assessment of saftey and efficacy of a new thrombolytic(ASSENT-2) trial[J].Circulation,2001,104(22):2653-2659.
  • 7de Lemos JA,Braunwald E.ST segment resolution as a tool for assessing the efficacy of reperfusion therapy[J].J Am Coll Cardiol,2001,38(5):1283-1294.
  • 8Purcell IF,Newall N,Farrer M.Change in ST segment elevation 60 minutes after thrombolytic initiation predicts clinical outcomes as accurately as later electrocardiographic changes[J].Heart,1997,78(5):465-471.
  • 9Zeymer U,Schrder K,Wegscheider K,et al.ST resolution in a single electrocardiographic lead:a simple and accurate predictor of cardiac mortality in patients with fibrinolysis therapy for acute ST-elevation myocardial infarction[J].Am Heart J,2005,149(1):91-97.
  • 10French JK,Ansdews J,Manda SO,et al.Early ST-segment resolution recovery,infarct artery blood flow,and long term outcome after acute myocardial infarction[J].Am Heart J,2002,143(2):265-271.

共引文献7

同被引文献81

引证文献12

二级引证文献44

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部