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ATF3在恶性肿瘤发生中作用的研究进展 被引量：1

The research progress on the role of ATF3 in the malignant tumor
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摘要 激活转录因子3（ATF3）是细胞在缺血-再灌注损伤、神经元或肝损伤、皮肤损伤、病毒癌基因表达或DNA损伤刺激下产生的一种蛋白质.近年来研究发现ATF3在人类多种恶性肿瘤发生、发展过程中发挥重要作用. Activating transcription factor 3 （ATF3） is a protein produced by the cells in the ischemic reperfusion injury,neuronal or liver damage,skin damage,viral oncogene expression or DNA damage.Recent studies have found that ATF3 plays an important role in the occurrence and development of human malignant tumors.
作者 于国华 张廷国
机构地区 青岛大学附属烟台毓璜顶医院病理科 山东大学齐鲁医院病理科
出处 《中国医师杂志》 CAS 2016年第8期1264-1268,共5页 Journal of Chinese Physician
基金 山东省自然科学基金青年基金资助项目（ZR2015HQ013） 烟台毓璜顶医院青年科研启动基金资助项目（201407）
关键词 转录激活因子3/代谢 肿瘤/代谢 综述 Activating transcription factor 3/ME Neoplasms/ME Review
分类号 R730.2 [医药卫生—肿瘤]
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参考文献43

  • 1BartkovaJ, HorejsíZ, KoedK, et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis[J]. Nature, 2005, 434(7035):864-870. DOI: 10.1038/nature03482.
  • 2GorgoulisVG, VassiliouLV, KarakaidosP, et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions[J]. Nature, 2005, 434(7035):907-913. DOI: 10.1038/nature03485.
  • 3YangH, ParkSH, ChoiHJ, et al. Epithelial cell survival by activating transcription factor 3 (ATF3) in response to chemical ribosome-inactivating stress[J]. Biochem Pharmacol, 2009, 77(6):1105-1115. DOI: 10.1016/j.bcp.2008.11.028.
  • 4HamdiM, PopeijusHE, CarlottiF, et al. ATF3 and Fra1 have opposite functions in JNK- and ERK-dependent DNA damage responses[J]. DNA Repair (Amst), 2008, 7(3):487-496. DOI:10.1016/j.dnarep.2007.12.004.
  • 5FanF, JinS, AmundsonSA, et al. ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth[J]. Oncogene, 2002, 21(49): 7488-7496. DOI: 10.1038/sj.onc.1205896.
  • 6HaiTW, LiuF, CoukosWJ, et al. Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers[J]. Genes Dev, 1989, 3(12B):2083-2090. DOI:10.1101/gad.3.12b.2083.
  • 7Darlyuk-SaadonI, Weidenfeld-BaranboimK, YokoyamaKK, et al. The bZIP repressor proteins, c-Jun dimerization protein 2 and activating transcription factor 3, recruit multiple HDAC members to the ATF3 promoter[J]. Biochim Biophys Acta, 2012, 1819(11-12):1142-1153. DOI: 10.1016/j.bbagrm.2012.09.005.
  • 8SekyrovaP, BohmannD, JindraM, et al. Interaction between Drosophila bZIP proteins Atf3 and Jun prevents replacement of epithelial cells during metamorphosis[J]. Development, 2010, 137(1):141-150. DOI: 10.1242/dev.037861.
  • 9GreenTA, AlibhaiIN, UnterbergS, et al. Induction of activating transcription factors (ATFs) ATF2, ATF3, and ATF4 in the nucleus accumbens and their regulation of emotional behavior[J]. J Neurosci, 2008, 28(9): 2025-2032. DOI: 10.1523/JNEUROSCI.5273-07.2008.
  • 10ShimizuM, NomuraY, SuzukiH, et al. Activation of the rat cyclin A promoter by ATF2 and Jun family members and its suppression by ATF4[J]. Exp Cell Res, 1998, 239(1):93-103. DOI: 10.1006/excr.1997.3884.

二级参考文献18

  • 1李军,王柯敏,谭蔚泓,刘斌,郭秋平,唐志文,刘凌风.分子信标荧光探针用于抑癌基因ING1表达产物的定量测定[J].高等学校化学学报,2004,25(3):421-424. 被引量：8
  • 2何春梅,王柯敏,刘斌,李军,唐志文,唐红星.人舌癌细胞耐药系Tca8113/BLM的建立及其耐药机理的分析[J].中国癌症杂志,2004,14(5):443-446. 被引量：8
  • 3HAI T, LIU F, COUKOS WJ, et al. Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers [J]. Genes Dev, 1989, 3: 2083-2090.
  • 4PELZER AE, BEKTIC J, HAAG P, et al. The expression of transcription factor activating transcription factor 3 in the human prostate and its regulation by androgen in prostate cancer [J]. .l Urol, 2006, 175(4): 1517-1522.
  • 5ISHIGURO T, NAKAJIMA M, NAITO M, et al. Identification of genes differentially expressed in B16 murlne melanoma sublines with different metastatic potentials[J]. Cancer Res, 1996, 56(4):875-879.
  • 6FAN F, JIN S, AMUNDSON SA, et al. ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth [J]. Oncogene, 2002, 21: 7488-7496.
  • 7BOTrONE FG, MOON Y, KIM JS, et al. The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3) [J]. Mol Cancer Ther, 2005, 4(5): 693-703.
  • 8KALFA N, LIU B, KLEIN O. Genomie variants of ATF3 in patients with hypospadias[J]. J Urol, 2008, 180(5): 2183-2188.
  • 9HUANG X, LI X, GUO B. KLF6 induces apoptosis in prostate cancer cells through up-regulation of ATF3 [J]. J Biol Chem, 2008, 283(44): 29795-29801.
  • 10YAN CH, LU D, HAI TW, et al. Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination[J]. EMBO Journal, 2005, 24(13): 2425-2435.

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中国医师杂志
2016年 第8期

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