中青年脑卒中生化危险因素的研究进展

Research progress on biochemical risk factors of stroke in young and middle-aged patients

脑卒中发病率逐年升高,约75％的患者遗留不同程度的后遗症,且发病年龄趋向年轻化,给社会和家庭带来沉重的负担.故加强研究中青年脑卒中相关危险因素,从而降低脑卒中发生率刻不容缓.传统的公认危险因素如高血压、糖尿病、高血脂、心脏病、肥胖及吸烟等能解释一部分脑卒中事件,对上述危险因素的干预性治疗明显地降低了脑卒中的发病率和死亡率,但并不能对心脑血管系统进行全面保护.鉴于患者血生化指标标本采取方便,指标检测简易准确,因此继续研究生化危险因素与中青年脑卒中发病的关系具有明确的必要性,且已成为目前脑卒中流行病学研究所面临的主要挑战.

The incidence of stroke is increasing year by year,about 75% of the patients with different levels of sequelae,and the age of onset also tends to be younger,to the community and the family to bring a heavy burden.Therefore,it is urgent to strengthen the study of the related risk factors of stroke in young people,so as to reduce the incidence of stroke.Traditional recognized risk factors such as hypertension,diabetes,high cholesterol,heart disease,obesity,and smoking can explain part of the stroke events,of these risk factors intervention treatment significantly reduced the incidence and mortality of stroke.However,cardio cerebral vascular system is not fully protected.In view of the biochemical indexes of blood of patients with specimens by convenience,detection index simple and precise,further studies of the relationship between biochemical risk factors and young stroke has made clear the necessity of and have become major challenges in current epidemiological study of cerebral stroke.