益生菌在肝硬化患者中的应用

Application of probiotics in patients with liver cirrhosis

肝硬化是各种慢性肝病发展的终末阶段,患者不同程度的存在肠道菌群失调。近年来随着肠-肝轴理论研究的深入,益生菌对肝硬化患者的作用受到越来越多的关注。研究表明,益生菌可有效改善肝硬化患者肝功能,并对预防肝性脑病的发生有积极作用。该文结合最近的临床研究,对肠道菌群失调临床特点、益生菌对肝硬化患者临床作用进行专题讨论。

Liver cirrhosis is a late-stage disease for a variety of chronic liver diseases. These patients may have different degrees of alteration of intestinal flora. With the establishment Of the bowel liver axis theory in recent years, probiotics, as an microecologics, get more and more attention at home and abroad. Many studies have shown that probiotics can effectively improve liver function in patients with cirrhosis. Probiotics has a positive role in the prevention of hepatic encephalopath. Combined with the recent clinical studies,we will focus on the clinical characteristics of alteration of intestinal flora and the treatment effects ofprobiotics in the patients with cirrhosis in this chapter.