CT早期梗死征象与急性脑梗死静脉rt-PA溶栓患者预后的关系

The relationship between CT signs and the prognosis of acute cerebral infarction intravenous thrombolysis in patients with rt-PA

目的 CT早期梗死征象与急性脑梗死静脉rt-PA溶栓患者预后的关系,为临床治疗策略的选择提供理论参考。方法选取我院神经内科接受静脉内溶栓治疗的急性脑梗死患者73例,其中预后好36例,预后差37例,平均年龄(68.13±9.36)岁。对其相关因素,如有无CT早期梗死征象、心房颤动、入院NIHSS评分等18个因素进行调查。结果在单因素分析中,CT检查无早期梗死征象组预后好的几率明显高于CT检查有早期梗死征象组(60%vs 24%,P=0.006)。在多因素Logistic回归分析中,在经心房颤动、糖尿病等因素调整后,有无CT早期梗死征象与急性脑梗死静脉rt-PA溶栓患者预后无显著相关。结论 CT早期梗死征象对急性脑梗死静脉rt-PA溶栓患者预后无独立影响。

Objective To study the relationship between CT signs and the prognosis of acute cerebral infarction intravenous thrombolysis in patients with rt-PA, and to provide a theoretical reference and clinical therapeutic strategies. Methods Seventy-three patients with acute cerebral infarction treated by intravenous thrombolytic therapy in Fourth Hospitals Affiliated to China Medical University were selected, including 36 patients with good prognosis, 37 patients with poor prognosis, aged （68.13± 9. 366） years old. Its related factors such as.. the CT signs, atrial fibrillation, admission NIHSS score and other factors of 18. Results In single factor analysis, the probability of no CT signs was significantly higher than CT signs with prognosis （60% vs 24% ,P=0. 006）, and in multiple logistic regression analysis, there was no significant correlation between CT signs and the prognosis of acute cerebral infarction intravenous thrombolysis in patients with rt-PA. Conclusion CT signs have no independent effect on the prognosis of patients with acute cerebral infarction with intravenous rt-PA thrombolysis.