血清组织蛋白酶S胱抑素C与急性动脉粥样硬化性脑梗死相关性分析

Study on the relationship between serum Cat S Cys C levels and acute atherosclerosis cerebral infarction

目的探讨急性动脉粥样硬化性脑梗死患者血清组织蛋白酶S(Cathepsin S,Cat S)和胱抑素C(Cystatin C,Cys C)水平的变化及临床意义。方法对336例急性脑梗死患者进行血清Cat S和Cys C检测,并与114例正常健康人作比较。结果急性动脉粥样硬化性脑梗死组患者与正常对照组进行比较,血清Cat S明显增高,而Cys C降低,差异均有统计学意义(P<0.05)。结论急性动脉粥样硬化性脑梗死患者血清Cat S与Cys C水平密切相关。

Objective To study of the the changes of serum Cat S and Cys C levels in patients with acute atherosclerosis cerebral infarction and its clinical significance. Methods The levels of serum Cat S and Cys C were measured in 336 patients with acute atherosclerosis cerebral infarction and 114 controls and were compared. Results Compared to controls the levels of serum Cat S were significantly higher in the patients and Cys C decreased obviously there was a significant difference（P〈0.05）. Conclusion Serum Cat S and Cys C levels might be highly correlated with acute atherosclerosis cerebral infarction.