锌离子荧光探针的最新研究进展

Recent Research Advances on Fluorescent Probes for Zn2

锌离子是生物体必需的微量元素之一,具有重要的生理功能,选择性识别和检测锌离子,对化学、生物学、临床医学和农学等领域的相关研究具有十分重要的意义。荧光探针分析法具有选择性好、灵敏度高以及操作简单等优势,因此设计合成锌离子荧光探针成为近几年的研究热点。本文基于不同母体化学结构,对近5年来锌离子荧光探针的研究进展进行了归纳总结,并对未来的发展提出了展望,旨在对后续锌离子荧光探针的进一步研究提供重要参考。

Zinc is an essential trace element whichhas an important physiological function in both plants and animals including human beings. Therefore, the detection and identification of zinc ion have vital significance to chemistry, biology, clinical medicine and agriculture. On the other hand, fluorescent probe method has good selectivity, high sensitivity and operational simplicity, the design of fluorescent probes for zinc ion has become an attractive research area in recent years. In this review, thedevelopment of fluorescent probes for zinc ion based on different chemical structures of matrix parent molecules reported in the last five years, has been summarized. In the end, future efforts to improve sensors＇ performance to meet growing needs are discussed.