泌尿系统念珠菌感染的菌种分布及药敏结果分析

Analysis on distribution and drug susceptibility resultes of candidiasis in urinary system

目的:分析泌尿系统念珠菌感染菌种的分布特征和药敏结果,为临床合理选药提供依据。方法:回顾性分析微生物实验室的中段尿培养结果,对念珠菌培养和药敏结果进行归纳总结。结果:在1 045株致病菌中93株为念珠菌,其中白念珠菌的比例最高(36/93,38.7%);主要来自50岁以上人群,女性(66.7%)多于男性(33.3%);阳性标本主要来自泌尿外科(29.0%)、ICU(23.6%)和神经内科(19.3%)。大部分菌株对氟胞嘧啶和两性霉素B有较高的敏感性。结论:泌尿系统念珠菌感染以白念珠菌为主。临床应根据药敏试验结果合理选择抗菌药物。

Objective： To analyze the distribution characteristics and drug susceptibility resultes of candida in urinary system in order to provide the basis for clinical rational drug use. Methods： The culture results of midstream urine in the microbiological lab were reviewed. Results of the cultivate and drug sensitivity to candida were summarized. Results： In 1 045 strains of pathogenic bacteria,93 strains were candida,in which accounts for the largest proportion was candida albicans（ 36 /93,38. 7%）. The patients infected with candidas were over the age of 50,and the amount of female（ 66. 7%） were more than that of male（ 33. 3%）. Positive specimens were mainly from the departments of urology（ 29. 0%）,intensive care unit（ 23. 6%）,and neurology（ 19. 3%）. Most of the strains had high sensitivity toward fluorine cytosine and amphotericin B. Conclusions： Candida albican is dominating bacterial strains in monilial infection of urinary system. Antibacterial agents should be rationally chosen according to the results of drug sensitive test.