2012—2015年北京医院抗菌药物应用分析

Utilization analysis of antibiotics in Beijing Hospital during 2012―2015

目的:通过对北京医院抗菌药物使用情况进行调查分析,为临床安全合理使用抗菌药物提供参考。方法:对2012―2015年抗菌药物的销售金额、用药频度(DDDs)和构成比,以及日均费用(DDC)等进行统计分析。结果:2012―2015年抗菌药物种类数呈现逐年下降的趋势,同时抗菌药物销售金额和DDDs虽然有所上升,但是占药品总销售金额的比例却逐年下降;4年中各类抗菌药物的用药金额和DDDs排序变化较小,销售金额大的品种相对固定,说明临床对常用抗菌药物的选择相对集中,其中头孢菌素类使用较多;绝大多数抗菌药物DDC持平或下调,同时使用频度高的药品相对来说DDC值较低。结论:北京医院对抗菌药物品种的选择和分级管理体现了有效性、安全性和多样性的特征,同时抗菌药物的使用较为合理,但也存在一些问题,需要改进。

Objective： To investigate and analyze the use of antibiotics in our hospital, so as to provide reference for clinical rational antibiotics use. Methods： The consumption sum, defined daily dose system （DDDs）, constituent ratio and defined daily cost （DDC） of antibiotics in our hospital were statistically analyzed during 2012-2015. Results： The variety number of antibiotics in our hospital showed a declining trend year by year during 2012-2015. Although the consumption sum and DDDs of antibiotics increased in our hospital, but the proportion of antibiotics decreased year by year. The consumption sum and DDDs of various antibiotics showed relatively few changes during the past four years, and the antibiotics with high consumption sum were relatively stable, which showed that the clinical selection of antibiotics were relatively concentrative and cephalosporins were Used more. DDC values of most antibiotics keeps stable or decreased, while the high DDDs drugs have relatively low DDC. Conclusion： The selection and classification management of antibiotics showed characteristic of effectiveness, safety and diversity, and the use of antibiotics were rational. However, there are still some problems needing improvements so as to guarantee safe, effective and economical clinic drug use.