女性不孕症患者生殖免疫抗体检测结果分析

Analysis of the reproductive immune antibody test results of female infertile patients

目的:分析女性不孕症患者生殖免疫抗体检测情况,为不孕患者的诊疗方案提供参考。方法:选取在我院不孕不育科和妇产科就诊的不孕女性患者2856例,采用酶联免疫吸附法(ELISA)检测各项生殖免疫抗体指标。结果:原发不孕组共442例(32.74%)患者生殖免疫抗体阳性,继发不孕组共594例(39.44%)患者生殖免疫抗体阳性。继发不孕患者生殖免疫抗体阳性率明显高于原发不孕组(P<0.05)。两组生殖免疫抗体阳性患者中,以单抗体阳性为主(71.95%vs.72.39%)。两组抗体分布统计学检验无显著差异(P>0.05)。结论:生殖免疫抗体阳性是影响不孕的原因之一,其中以单阳性抗体为主,且继发不孕患者阳性率高于原发不孕。

Objectives： To analyze the reproductive immune antibody detection results of female infertile patients,in order to provide reference for the treatment. Methods： 2856 female infertile patients in our hospital were selected and the reproductive immune antibody indicators were detected with enzyme- linked immunosorbent assay（ ELISA）. Results： There were 442 cases（ 32. 74%） and 594（ 39. 44%） cases of positive antibodies in the primary infertility group and secondary infertility group respectively,with statistically significant difference（ P〈0. 05）. In patients with positive antibody,the majority was single antibody positive（ 71. 95% vs. 72. 39%）,without statistically significant difference between the two groups（ P〉0. 05）. Conclusions： Positive reproductive immunology antibody is one of the causes of infertility,the majority of which is single positive antibody,and the positive rate in patients with secondary infertility is higher than those of primary infertility.