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探讨动态监测C-反应蛋白联合血液培养在诊断菌血症中的应用价值

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摘要 目的评估动态监测C-反应蛋白联合血液培养在预示菌血症中的价值。方法选取2012年3月-2014年8月入院疑似菌血症的患者,收集其入院治疗前、使用抗菌药物24h、72h的血清进行C-反应蛋白检测,并进行血液培养,排除污染生长情况,纳入研究的血液培养阳性47例,并收集30例正常人的血清作为对照。同时对研究对象的C-反应蛋白进行统计学处理。结果 47例患者在入院治疗前、使用抗菌药物24h和72h三个时间点的C-反应蛋白血清浓度无明显差异(P>0.05),但与正常对照组相比其差异均具有显著性意义(P<0.05)。其血液培养共检出革兰阴性杆菌42例,革兰阳性球菌5例,将患者分为革兰阴性菌组和革兰阳性菌组,各组血清C-反应蛋白浓度在三个时间点相互比较无明显差异(P>0.05)。结论连续监测C-反应蛋白可以有助于菌血症的诊断,可作为血培养的重要补充指标,对于病情的诊断具有一定的临床应用价值。
出处 《实验与检验医学》 CAS 2016年第4期501-503,共3页 Experimental and Laboratory Medicine
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