美罗培南治疗老年卒中相关性肺炎的效果及安全性分析

Analysis of the Effect of Meropenem in the Treatment of Pneumonia in Elderly Stroke and Safety

目的探究美罗培南治疗老年卒中相关性肺炎的临床效果及安全性。方法选取86例来我院治疗的老年卒中相关性肺炎患者,随机分为甲、乙两组。常规治疗基础上,甲组患者给予美罗培南联合氯化钠溶液治疗,乙组患者给予头孢他啶联合氯化钠溶液治疗。对比观察两组患者治疗效果及不良反应发生情况。结果甲组患者总体有效率为97.67%,乙组为86.05%,甲组高于乙组(P<0.05),甲组患者不良反应发生率低于乙组(P<0.05)。结论老年卒中相关性肺炎患者采用美罗培南进行治疗能提高治疗效果,且不良反应少。

Objective The clinical efficacy and safety of meropenem in the treatment of elderly stroke associated pneumonia. Methods 86 elderly patients with stroke associated pneumonia in our hospital were randomly divided into two groups. On the basis of conventional therapy, patients with first given meropenem combined with sodium chloride solution treatment, the patients of group B were given ceftazidime ceftazidime combined with chloride sodium solution treatment. The treatment effect and adverse reaction of the two groups were compared and observed. Results Patients with a total efficiency was 97.67%, group B was 86.05%. Group A were higher than those in group B（P〈0.05）, and the adverse reactions in patients with first division occurrence rate is lower than group B（P〈0.05）. Conclusion Elderly patients with stroke associated pneumonia using meropenem for treatment can improve the therapeutic effect, and less adverse reactions.