慢性阻塞性肺疾病急性加重期的临床治疗

Research on the Clinical Therapy in Patients With AECOPD

目的 探讨慢性阻塞性肺疾病急性加重期的临床治疗。方法 选取48例于2015年4月-2016年4月我院接收的慢阻肺急性加重期患者,根据治疗方式不同分为对照组（常规治疗）与实验组（常规治疗＋糖皮质激素＋吸入用复方异丙托溴铵溶液）,观察两组疗效。结果 实验组较对照组临床疗效要佳（P〈0.05）;同时实验组住院时间短于对照组（P〈0.05）;此外,治疗3-7 d后,两组血气指标均有改善,但实验组在PaO2、PaCO2的改善优于对照组（P〈0.05）。结论 糖皮质激素＋吸入用复方异丙托溴铵溶液可改善COPD急性加重期患者病情,疗效较佳,适用于临床治疗,且安全性较高。

Objective To study the clinical therapy in patients with AECOPD（acute exacerbation of chronic obstructive pulmonary disease）. Methods 48 AECOPD patients treated from April 2015 to April 2016 in our hospital were selected. The subjects were divided into two groups according to different therapies. The control group adopted the conventional therapy,and the test group adopted the conventional therapy,glucocorticoid and inhalation of ipratropium bromide solution. The clinical effect for two groups was observed. Results The clinical effect for test group was better than that of control group（P〈0.05）. The hospitalization time for test group was shorter than that of control group（P〈0.05）. After 3 to 7 d of treatment,the blood gas index for two groups was improved. The index of PaO2 and PaCO2 for test group was better than that of control group（P〈0.05）. Conclusion The glucocorticoid and inhalation of ipratropium bromide solution has an obvious effect in patients with AECOPD,can improve the clinical safety.