肾小球肾炎中医辨证与检验指标相关意义

The Correlation Between TCM Syndrome Differentiation and Test Index of Glomerular Nephritis

目的 分析肾小球肾炎患者的中医辨证和检验指标的关联性。方法 对48例肾炎患者的Lee氏病理损害分级和患者的Katafuchi半定量积分进行统计分析和对比。结果 本研究中Lee氏病理损害分级为Ⅱ-Ⅲ级的患者中脾肾阳虚型所占比例最大,占57.14%。Lee氏病理损害分级为Ⅳ-Ⅴ级的患者中肝肾阴虚型所占比例最大,占44.44%。气阴两虚型患者在Ⅱ-Ⅲ级与Ⅳ-Ⅴ级中所占比例的差异无统计学意义（χ^2=0.03,P〉0.05）。肝肾阴虚型患者在肾小球、肾小管间质以及肾血管Katafuchi半定量积分均显著高于脾肾阳虚型和气阴两虚型患者（P均〈0.05）,且肝肾阴虚型患者Katafuchi半定量总积分最高。结论 肾小球肾炎中医辨证与临床相关检验指标存在相关性,可将中医辨证作为临床诊断和治疗依据,帮助患者改善病情,提高预后效率。

Objective To study the correlation between TCM syndrome differentiation and test indexes in patients with glomerular nephritis. Methods Statistical analysis and comparison were made on the Lee＇s pathological grading and Katafuchi semi quantitative score of 48 patients with nephritis. Results The results of this study Lee＇s pathological grade II - III patients with spleen deficiency type accounted for the largest proportion,accounting for 57.14%. Lee＇s pathological damage grade IV - V grade in patients with liver and kidney yin deficiency type accounted for the largest proportion,accounting for 44.44%. In patients with Qi and yin deficiency type of grade II - III and IV - V in the proportion of no significant difference（χ^2=0.03,P〉0.05）. Liver and kidney yin deficiency type patients in renal glomerulus and renal tubule matter and renal vascular project katafuchi semi quantitative scores were significantly higher than those in patients with Yang deficiency of spleen and kidney and deficiency of both qi and Yin type（P〈0.05）and yin deficiency of liver and kidney of patients katafuchi semi quantitative score the highest. Conclusion There is a correlation between glomerular nephritis with TCM syndrome differentiation and clinical test indicators,syndrome differentiation of traditional Chinese medicine as a basis for clinical diagnosis and treatment can help patients to improve the condition,and at the same time,improve the efficiency of the prognosis of patients.