颈动脉超声评估颈动脉粥样硬化斑块易损性的临床应用研究

Clinical Application of Carotid Artery Ultrasound in the Evaluation of the Vulnerability of Carotid Atherosclerosis Plaque

目的探析颈动脉粥样硬化斑块易损性,应用颈动脉超声评估的临床应用观察研究。方法临床选择2013年5月至2015年5月本院收治的颈动脉粥样斑块病人50例为观察组,同期入选体检健康者50例为研究对照,均进行颈动脉超声检查,比较两组颈内动脉的PI、RI、S/D指标;比较两组的增强密度(DE)、达峰时间(TTP)等临床指标;评估不同部位的增强斑块比率。结果观察组的PI、RI、S/D指标显著低于对照组,差异有统计学意义(P<0.05);观察组的增强密度(DE)、达峰时间(TTP)等临床指标显著高于对照组,差异有统计学意义(P<0.05);肩部的增强斑块比率显著高于基底部、尾部,差异有统计学意义(P<0.05)。结论颈动脉粥样硬化斑块应用颈动脉超声检查可早期评估其易损性,临床效果确切,值得临床推广。

Objective To study the clinical application of carotid artery ultrasound in the evaluation of the vul- nerability of carotid atherosclerosis plaque. Methods 50 patients with carotid atherosclerosis plaque treated from May 2013 to May 2015 in our hospital were selected as observation group. 50 healthy check- ups were selected as control group. Both of groups adopted the carotid artery ultrasound. The index ofPI, RI and S/D as well as DE and TTP for two groups was compared. The enhancement ratio of plaque for different body parts was evalu- ated. Results Theindex of PI, RI and S/D for observation group was significantly lower than that of control group （P 〈 0.05） ; The index of DE and TTP for observation group was significantly higher than that of control group（P〈 0.05）; The enhacement ratio ofplaque in the shoulder was significantly higher than that of basilar part and afterbody（P 〈 0.05）. Conclusion The carotid artery ultrasound has an obvious effect in theearly eval- uation of the vulnerability of carotid atherosclerosis plaque. It is worthy of clinical promotion.