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糖代谢异常患者颈动脉斑块形成的危险因素分析 被引量:1

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摘要 目的探讨糖代谢异常人群颈动脉斑块的相关危险因素。方法选取行颈动脉超声的住院患者240例,按糖代谢是否正常分为糖代谢正常组和糖代谢异常组,按颈动脉是否有斑块分为有斑块组与无斑块组,分析颈动脉斑块形成的影响因素尤其是糖代谢异常人群颈动脉斑块形成的相关危险因素。结果 240例患者中有颈动脉斑块142例(59.17%),糖代谢异常160例(66.67%),糖尿病89例。糖代谢异常组发生颈动脉斑块是糖代谢正常组的1.979倍(95%CI 1.069-3.663,P〈0.05),糖尿病人群则高达3.103倍(95%CI 1.577-6.106,P〈0.01),而糖调节受损人群OR值是1.453(95%CI 1.014-2.082,P〈0.05)。年龄(OR=1.060,95%CI 1.012-1.110,P〈0.05)是糖代谢正常人群颈动脉斑块形成的独立危险因素,而糖代谢异常人群颈动脉斑块形成的独立危险因素除了年龄(OR=1.063,95%CI 1.028-1.099,P〈0.01)之外,还包括HOMA-IR(OR=1.511,95%CI1.159-1.971,P〈0.01)。结论糖代谢异常住院患者颈动脉斑块发生率高。糖代谢异常是颈动脉斑块形成的独立危险因素。年龄、HOMA-IR是糖代谢异常人群颈动脉斑块形成的危险因素。糖代谢水平的筛查可作为预防颈动脉斑块形成的重要方法。
出处 《山东医药》 CAS 北大核心 2016年第29期50-53,共4页 Shandong Medical Journal
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