输注病毒灭活血浆、新鲜冰冻血浆和冷沉淀对新生儿凝血功能的影响分析

Influencing Analysis of Effect of Virus Inactivated Plasma,Fresh Frozen Plasma and Cryoprecipitate on Newborn Coagulation Function

目的回顾性分析对凝血功能异常的新生儿输注病毒灭活血浆、新鲜冰冻血浆、和冷沉淀对新生儿凝血功能的影响与临床表现因素分析。方法对进行凝血治疗的新生儿按照不同病因进行分组分析,观察分析其变化。结果凝血功能异常的新生儿临床表现因素：宫内窘迫、新生儿肺炎、酸中毒、低体温的比例均高于凝血功能正常的新生儿,差异有统计学意义（χ2=6.19~38.00,P〈0.05）。结论使用新鲜冰冻血浆和冷沉淀提前干预治疗可减少新生儿凝血性疾病的发生。

Objective To explore the effect of virus inactivated plasma,fresh frozen plasma and cryoprecipitate on newborn coagulation function. Methods Newborns under coagulation treatment were analyzed according to different pathogenesis. Results The rate of intrauterine poverty- stricken,pneumonia,acidosis and hypothermia of newborns with abnormal coagulation function is higher than the newborns with normal coagulation function,with statistical significant difference（ χ2= 6. 19 ~ 38. 00,P〈0. 05）. Conclusion Fresh frozen plasma and cryoprecipitate can effectively improve the incidence of neonatal hemorrhagic disease.