口腔益生菌与口腔常见疾病的关系

Relationship between probiotics and oral diseases

人体口腔是一个存在多种微生物的复杂的微生态系统。正常的口腔中大约寄宿着上千种不同的细菌。口腔菌群一旦失调就会导致口腔疾病的出现，例如龋齿、牙周病长期困扰着患者和临床医生，而传统的预防治疗方法又存在种种弊端。乳酸杆菌是广泛应用的益生菌，在调节胃肠道生态平衡方面发挥重要作用，在口腔疾病的预防方面国内外学者也进行了大量的研究。此文对最近几年关于口腔乳酸杆菌的研究应用、作用机制以及应用前景做一概述。

Human oral cavity is a complicated microecosystem with thousands of different kinds of bacteria in the healthy mouth environment. The disorder of oral flora will lead to oral diseases, such as dental caries and periodontal disease, which perplex the patients and clinicians for a long time. Traditional prevention and control methods of oral diseases have many drawbacks, so the new treatment of lactobacillus is getting noticed. Lactobacillus is a widely used probiotic, which plays an important role in maintaining ecological balance in intestinal tract as well as in oral cavity. The recent studies on the mechanism and application prospect of oral lac, tobacillus are summarized in this article.