宫腔粘连与子宫内膜容受性

Intrauterine adhesion and endometrial receptivity

宫腔粘连是临床常见的难治病,严重影响育龄期女性患者的身心健康及生育能力。子宫内膜容受性是影响胚胎着床的重要因素之一。宫腔粘连可以从形态学及分子生物学等方面影响子宫内膜容受性,其中形态学改变主要包括微观结构胞饮突的改变及超声下内膜相关参数的改变。现代医学已有不少提高宫腔粘连患者子宫内膜容受性的方法,但尚缺乏统一的治疗规范。

Intrauterine adhesion is common refractory disease, and seriously affects the physical and mental health and fertility of women with childbearing age. Endometrial receptivity is one of the important factors affected embryo implantation. Intrauterine adhesion have an influence on endometrial receptivity confirmed by the morphological and molecular biology studies. The morphological changes include the microstructure of pinopodes and ultrasound parameters of endometrium. There are many methods of modern medicine for improving endometrial receptivity of patients with intrauterine adhesion, but lack of uniform treatment guidelines.